Medically reviewed by Dr. Rao Khurram Ayoub, RPh, PhD (Pharmaceutics)
Updated on
QTc Prolongation Risk Calculator
Enter QT interval, heart rate, sex, and medicines to estimate QTc and identify QT-prolonging drugs.
QTc correction and risk thresholds are educational only; this tool does not replace ECG interpretation or clinical judgment [web:168][web:169][web:172][web:173][web:174].
- The QTc Prolongation Risk Checker helps clinicians and patients assess the likelihood of QT interval prolongation, a condition that can lead to dangerous arrhythmias such as torsade de pointes. Using the Tisdale Risk Score, the tool combines clinical factors (age, sex, electrolyte imbalance, comorbidities) with a curated list of QT‑prolonging medications including amiodarone, sotalol, haloperidol, citalopram, macrolides, fluoroquinolones, and ondansetron.
- By integrating CredibleMeds QTDrugs list and FDA drug label warnings, the checker provides evidence‑based guidance for safer prescribing. Results are displayed as low, moderate, or high risk categories, helping clinicians make informed decisions and patients understand their medication safety.
Refrences:
https://europepmc.org/article/MED/23716032Tisdale, J.E., Jaynes, H.A., Kingery, J.R., et al. (2013). Development and validation of a risk score to predict QT interval prolongation in hospitalized patients. Journal of the American College of Cardiology, 61(8), 1043–1050.
Drew, B.J., Ackerman, M.J., Funk, M., et al. (2010). Prevention of torsade de pointes in hospital settings: A scientific statement from the American Heart Association. Circulation, 121(8), 1047–1060.
CredibleMeds (2025). QTDrugs List. Available at:
https://www.crediblemeds.org